Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction.
نویسندگان
چکیده
منابع مشابه
Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12.
The 21,000-dalton protein (p21) encoded by the ras oncogene of Harvey murine sarcoma virus (v-Ha-ras) becomes phosphorylated (pp21) in vivo and in vitro on threonine residue 59. p21 molecules encoded by cellular ras genes (c-Ha-ras-1) contain an alanine at position 59, and thus these p21 molecules are not phosphorylated. In this investigation, recombinant ras genes have been constructed between...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1988
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)37854-2